Parathyroid Pathology

Parathyroid Pathology Update

The microscopical pathology of primary parathyroid hyperplasia.

The microscopical pathology of the two types of primary parathyroid hyperplasia is reviewed. The importance of the differential diagnosis between chief cell hyperplasia and adenoma is stressed. The problems of the surgical pathologist in masking this differential diagnosis of a biopsy, especially on a frozen section sample, are discussed.

Thyroid and parathyroid gland pathology. Role of imaging.

There are many imaging modalities available for studying thyroid and parathyroid masses. For the thyroid gland, the demonstration of a hyperfunctioning or purely cystic mass by scintigraphy and ultrasound reassures that a palpable nodule is not cancer. Solitary, cold, or solid nodules often requires biopsy because of suspicion of malignancy. Metabolic and inflammatory disorders are imaged best ...

Highly aggressive pathology of non-functional parathyroid carcinoma

Parathyroid carcinoma is a rare malignant endocrine tumor accounting for only 0.5% to 5% of all primary hyperparathyroidism. Among these malignancies, only 10-25% are nonfunctioning. After the review of the literature we could only ascertain a number of 25 cases reported worldwide, since 1929, our case being the 26th, but the first with a very aggressive pathology, treated with chemotherapy sch...

Simultaneous Dual-Isotope SPECT Imaging for the Detection and Characterization of Parathyroid Pathology

V a r i o u s imaging methods have been used for the preoperative localization of parathyroid tumors in patients with hyperparathyroidism. Among the noninvasive methods, several scintigraphic techniques have been employed, including variations on the dual-isotope 2°ITI/99mTC subtraction techniques (1-3). Modification of this technique, using 123I instead of [99mTC] pertechnetate, has also been ...